“Almost exactly two years ago, WHO recommended the broad use of the world’s first malaria vaccine called RTS,S,” WHO chief Tedros Adhanom Ghebreyesus told a briefing in Geneva.
“WHO is now reviewing the vaccine for prequalification, which is WHO stamp of approval, and will enable GAVI and UNICEF to buy the vaccine from manufacturers,” Tedros said.R21/Matrix-M is mass manufactured by Serum Institute of India and uses Novavax’s Matrix M adjuvant. The vaccine will compete against the RTS,S shot by GSK Plc , which was recommended by the United Nations-agency in 2021 and sold under the brand Mosquirix.
“GSK has always recognised the need for a second malaria vaccine, but it is increasingly evident that RTS,S, the first ever malaria vaccine and the first ever vaccine against a human parasite, set a strong benchmark,” GSK said in a statement. Takeda’s vaccine was shown in trials to be effective against all four serotypes of the virus in people who were previously infected by dengue, Hanna Nohynek, chair of WHO’s Strategic Advisory Group of Experts on Immunization, told journalists.
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