Most Influential Companies 2023: Colossal Biosciences

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It’s been 4,000 years since the woolly mammoth went extinct, but Dallas-based Colossal Biosciences wants to change that. Find out how the company became one of the most influential of the year

t’s been 4,000 years since the woolly mammoth went extinct, but Dallas-based Colossal Biosciences wants to change that. In 2022, it announced it had sequenced the genome of the Asian elephant, which shares 99.6% of its genes with the woolly mammoth. Combining that with DNA samples from mammoth remains could mean a rebirth of the species. The company hopes to work its “de-

” magic on other species, including the dodo and the Tasmanian tiger, and threatened species could be saved from extinction by editing more diversity into their genomes, making them more robust.

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