Stocks making the biggest moves midday: Autodesk, Broadcom, AMC Networks, Virgin Galactic and more

Check out the companies making headlines in midday trading. Virgin Galactic – The struggling space company slid 15% as the stock's 1-for-20 reverse stock split took effect. The company was trying to get its stock back above $1 a share after a steady slide over the last three years. Virgin Galactic paused spaceflight operations this year to focus resources on developing its next-generation Delta-class spacecraft .

Shattuck Labs – The biotechnology stock dropped 14% on the back of a BTIG downgrade to neutral from buy. Though clinical trial data released Friday shows "encouraging efficacy," BTIG said there's "ambiguity" in one area that should remain unresolved until the second half of 2025. Louisiana-Pacific – Shares of the building materials manufacturer fell more than 5% after Goldman Sachs downgraded the stock to sell from neutral.

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