5 things to know before the stock market opens Tuesday

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Here are the most important news items that investors need to start their trading day.

Amgen's experimental weight loss drug, MariTide, helped some patients in a mid-stage trial lose up to 20% of their body weight.on President-elect Donald Trump's selection for Treasury secretary, Scott Bessent, the founder of Key Square Group. The Dow added 440 points, or nearly 1%; the S&P advanced 0.3%; and theadditional tariffs of 10% on all goods from China and 25% on goods from Canada and Mexico once he takes office. The levies would end a free trade agreement with the U.S.

and Kohl's lowered its full-year sales forecast. The reports come days ahead of the key Black Friday shopping event.The data was on the lower end of Wall Street's projections and comes from part one of a two-part phase two trial designed to test dose sizes, schedule and regimen of the drug.

– CNBC's Alex Harring, Hakyung Kim, Evelyn Cheng, Gabrielle Fonrouge, Melissa Repko, Jacob Pramuk, Annika Kim Constantino and Yun Li contributed to this report.

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