Moderna coronavirus vaccine, 5 burning questions after first results - Business Insider

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We just got our first human results for a coronavirus vaccine. Here are the 5 biggest questions we still need answered about Moderna's injection.

The upstart biotech Moderna has led the world in quickly developing a COVID-19 vaccine candidate, called mRNA-1273. The company was the first to start clinical testing and the first to release early human results.

Moderna executives characterized Monday's results as showing the vaccine is safe and tolerable. But researchers observed severe side effects in several of the first 45 volunteers. Larger trials will start soon that test Moderna's serum in hundreds and thousands of people. But if 1 in 10 people — or a higher proportion — experience a severe side effect, that may raise some doubts about the candidate. 'Crazy hours, short nights': The inside story of how a buzzy biotech upstart developed a potential coronavirus vaccine in record timeThis question is best answered by large-scale trials that can compare a group of vaccinated people to a group given a placebo.

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