5 things to know before the stock market opens Wednesday

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Here are the most important news items that investors need to start their trading day.

Wednesday over the company's failure to get approval before closing its deal to buy Grail. Illumina's acquisition of the cancer test developer has been trouble since the deal closed in 2021. It sparked a fight with activist investor Carl Icahn, while Francis deSouza abruptly quit as CEO in May despite surviving a proxy vote. Illumina's market value has also tumbled to about $29 billion today from around $75 billion when the Grail deal was finalized.

Ukraine President Volodymyr Zelenskyy wants stronger guarantees from NATO as his country remains under attack by Russian forces. While the U.S. and other Western nations have poured aid into Ukraine's effort to defend itself against Vladimir Putin's military, Zelenskyy wants his nation to join NATO, which considers an attack on one of its members an attack on all of them.

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