Undisclosed industry payments rampant in drug-trial papers

Publicly accessible and government-run databases have helped to expose financial ties between the pharmaceutical industry and medical researchers mainly in the United States, where drug companies and device manufacturers have been legally required to report payments to health-care providers since 2014.

Despite this public scrutiny, evidence suggests that medical researchers are continuing to under-report conflicts of interest, which undermines integrity in science, says Cameron Taheri, a physician-researcher at the University of Calgary in Canada. A 2021 meta-analysis of mostly US studies , led by Taheri, found that, on average, two-thirds of clinical-trial authors omitted at least one financial conflict in published works.Part of the problem is probably the inconsistent reporting requirements across journals and unclear instructions about what constitutes a relevant conflict of interest, says Adam Dunn, a clinical-research informatician at the University of Sydney.

But Mintzes suspects the problem lies more with individual researchers than with journals, although the latter not enforcing their disclosure policies could be an issue.

Mintzes says the results probably underestimate the extent of under-reporting of conflicts of interest because the analysis relies on the industry-run Medicines Australia database, which trial collates payments. Only member companies of Medicines Australia are required to report funds paid to health professionals.

Does science matter? Despite all the science behind COVAXIN, US_FDA keeps pushing it back. I wouldn’t be surprised if FDA is requesting the fingerprints of the 300M+ people who have taken COVAXIN while approving big pharma vaccines with less data/support. IchooseCOVAXIN

That is very disturbing.

Pharma. Destroying innovation, lying about R&D, promoting often shitty drugs, holding effective meds ransom causing global millions great suffering and death. Put execs in prison for their acts of economic genocide.

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