Biotech Companies Seek to Restore Functions to Spinal-Cord Injury Patients

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Biotech companies and researchers are studying treatments that could help patients with spinal-cord injuries recover abilities to move and function that they've lost. Finding a successful treatment could spur more research and investment in the field.

Each year about 18,000 Americans suffer spinal-cord injuries, which are often caused by automobile accidents, falls, violence and sports injuries, according to the National Spinal Cord Injury Statistical Center. Depending on the injury, patients can lose some or all sensation and control of movement below the injured section of the spinal cord.

Venture investors are financing startups such as ReNetX Bio Inc. and EG 427 that are developing biotech treatments that could help patients regain functions and live more independently, adding to the research physicians and academic scientists are conducting. Some studies of gene, protein and cell therapies being pursued by biotech and academic researchers have shown promise in animal and early-stage human studies.

Scientists seeking to reverse the damage caused by spinal-cord injuries have had to contend with obstacles such as the complexity of the condition and the relative lack of federal and investor funding for this research. “It is like the silent or invisible disease,” said Richard G. Fessler, a neurosurgeon at Rush University Medical Center who has been involved in cell-transplant clinical research. “Everybody’s afraid they are going to get cancer. Nobody thinks they are going to get a spinal-cord injury.”

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