– Horizon soared 32.9% in off-hours trading after the drug maker said it was in preliminary talks about a possible sale with several large pharma companies, including Amgen , Sanofi and Johnson & Johnson's Janssen Global Services unit.State Street added 3.5% in premarket action after announcing an agreement to terminate its planned $3.5 billion purchase of Brown Brothers Harriman's Investor Services unit.
State Street cited difficulties in gaining the approval of regulators for the deal.Biogen shares rose 3.6% in premarket action after partner Esai said it believed two deaths in the trial of their experimental Alzheimer's drug could not be attributed to the treatment. Biogen stock fell earlier in the week when the report of the second death first surfaced. Data from the trial showed that the drug slowed cognitive decline but could carry a risk of serious side effects.
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