Genentech Alzheimer's drug gantenerumab fails 2 late-stage clinical trials - San Francisco Business Times

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Genentech Alzheimer's drug gantenerumab fails 2 late-stage clinical trials - San Francisco Business Times
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Late-stage Alzheimers trials from Genentech/Roche fail; company pauses enrollment in prevention study with same drug

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An experimental drug that Genentech Inc. and parent company Roche had hoped would clear away clumps of proteins in the brains of Alzheimer's Disease patients failed two late-stage clinical trials.

Gantenerumab, Genentech's monoclonal antibody, had failed a previous Phase III study with Genentech drug-discovery partner MorphoSys. The trials focused on people with mild cognitive impairment due to Alzheimer's and with mild Alzheimer's dementia.

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