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PayPal and Dropbox stocks fall after downgrades, GM shares inch higher, and more stocks on the move

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Here are some of the most notable stock movers ahead of Monday's Wall Street open.

MariaDB PLC shares MRDB, -1.36% jumped 9% in premarket trading on Monday after venture capital group Runa Capital said Friday it had offered to buy the system software group for 56 cents a share in cash, representing a premium of around 24% based on the Sept. 13 closing price for MariaDB shares.

DoorDash Inc. shares DASH, -2.47% were rising more than 2% in premarket trading Monday after Mizuho upgraded the stock to buy. Iovance Biotherapeutics Inc. IOVA, +13.46% shares jumped 7.7% in premarket trading. Shares of the biotechnology company were building on gains seen last Friday after the U.S. Food and Drug Administration agreed to expedite the remaining review of its Biologics License Application for lifileucel, a melanoma-treatment drug.Axcella Health Inc. shares AXLA, -38.23% fell 10%. Shares slumped Friday after the biotech company announced plans for a 1-for-25 reverse stock split.

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