Biotech Company Says It's Implanted Dopamine-Making Cells in Patients' Brains

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A California-based biotech company says it has successfully implanted lab-made neurons in Parkinson's patients' brains to stimulate dopamine.

A California-based biotech company says it's successfully implanted lab-made neurons in Parkinson's patients' brains to stimulate a dopamine response — and if it works as intended, it could be a substantial advance in fighting the disease., the early stem cell experiment, which was meant to test whether the procedure is safe, appears to have succeeded at that goal.

Brain scans from the experiment's subjects show, the report notes, both an increase in dopamine cells and a decrease in times when the patients felt "off" or incapacitated by their symptoms. As, the study's leaders told the Copenhagen conference that the "off time" was lower for those patients who had been given higher doses of the experimental stell-cell neurons.

But according to Roger Barker, a University of Cambridge Parkinson's expert who was not involved in the study, the current results are a "bit disappointing." Nevertheless, "it is encouraging that the trial has not led to any safety concerns and that there may be some benefits," the Cambridge researcher toldWhile there is medication to help control Parkinson's symptoms, there is no cure for the progressive disorder that leads to increasing motor difficulties and causes tremors and limb rigidity.

 

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