that characterized lysosome-targeting chimeras, or LYTACs.
This new class of molecules bind both the extracellular domain of a target protein and a cell-surface receptor involved in the lysosomal degradation pathway. In the presence of a LYTAC, the activated M6PR tags and drags the target protein to its degradation.
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CarolynBertozzi LyciaTx Palleon_Pharma CatalentPharma Quite literally the best definition of 'over-achiever' I've ever seen. good job to her!