Stocks making the biggest moves midday: Dollar Tree, Amazon, FedEx and more

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These are the stocks posting the largest moves in midday trading.

— Shares of Dollar Tree popped more than 3% after the discount retailer reiterated its fiscal second-quarter 2023 earnings guidance. The company expected quarterly earnings between 79 cents per share and 89 cents per share. It also maintained its full-year outlook for the fiscal year.

— The Netherlands-based gene therapy stock dropped 38.7% after the company gave an update on a late-stage trial for a potential therapy for Huntington's Disease. On Tuesday, the company said it hit a $100 million milestone related to its first commercial sale of Hemgenix, which is used in the treatment of adults with hemophilia B.

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