Stocks making the biggest moves midday: CSX, Nu Skin, Ralph Lauren, Seattle Genetics & more

— Shares of the online brokerage fell 2.4% after reporting disappointing 2019 Q2 earnings. The company's second quarter earnings-per-share were 46 cents. Analysts polled by Refinitiv expected a profit of 53 cents per share. The company's results were impacted by lower trading commissions and an 8% rise in expenses.

— Seattle Genetics rose over 18% as investors cheered record sales of Adcetris, a drug used to treat Hodgkin's lymphoma. The company said Adcetris generated $159 million in U.S. and Canada sales. The Adcetris overshadowed mixed quarterly results. Piper Jaffray raised the company's stock to overweight from neutral, citing the drug's strong performance.

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