Johnson & Johnson Vaccine Trial Paused Due To 'Unexplained Illness' In Participant

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The company said it had paused further dosing in all of its COVID-19 vaccine candidate clinical trials while it investigated the volunteer's illness.

In a conference call on Tuesday morning to discuss the company's finances, Johnson & Johnson said it had learned on Sunday evening about the participant's illness, and it had informed an independent data and safety monitoring board immediately.

Mathai Mammen, who leads global research and development at Janssen, Johnson & Johnson's pharmaceutical division, said on the call that the company does not yet know whether the participant had received the vaccine or a placebo. The independent safety board has the right to unblind the study, Mammen said, but the company remains blinded for now.

"We know very little at this point, and it will be a few days at minimum for the right set of information to be gathered and evaluated," he said. Details about the nature of the illness were not provided. Johnson & Johnson's pause isn't the first time a COVID-19 vaccine trial has been halted due to health safety concerns. Last month, the Phase 3 trial of a vaccine candidate from AstraZeneca

 

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