BioNTech initiates clinical trial of mRNA-based malaria vaccine candidate

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BioNTech has initiated a first-in-human Phase 1 clinical trial of its BNT165b1 malaria vaccine candidate using mRNA technology, the German company announced on Friday.

The Phase 1 trial is expected to enrol 60 volunteers in the United States with no history of malaria to evaluate the vaccine candidate at three dose levels, BioNTech said in a statement.

The company said it will initially evaluate different antigens of the parasite that causes malaria over the coming months to help select the multi-antigen vaccine candidate with which to proceed to later-stage trials.

 

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