Fractional dosing could maximise the number of doses that can be administered currently, without compromising protection, says the UK Health Security Agency .
Clinics in Chelsea and Westminster NHS Trust, Central and North West London NHS Foundation Trust and Locala Health and Wellbeing in Greater Manchester are to begin offering people the lower dose option.
"We will continue to remain agile in our response to the monkeypox outbreak and will adapt our approach as new science and advice becomes available." Dr Claire Dewsnap, President of the British Association for Sexual Health & HIV, said: "We absolutely support the UKHSA-led fractional dosing pilots assessing feasibility in UK sexual health clinics. If acceptable, this would offer us the opportunity to roll out vaccine to those eligible much faster, and would address the issues of short supply of vaccine across the world."