Moderna Says Its COVID Vaccine Works in Kids Under 6

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Moderna said that interim results from its clinical trial showed that children 6 months to 5 years old had an immune response similar to what was observed in previous trials of young adults ages 18 to 25

Elena Rosales gets applause while checking out her new Band-Aid after receiving her shot during Moderna’s COVID-19-vaccine trial on December 7, 2021. Photo: Brian Cassella/Chicago Tribune via Getty Images In another step forward on the long road to a COVID-19 vaccine for young kids, Moderna announced on Wednesday that its vaccine generated a strong immune response in children 6 months to 5 years old.

However, the regimen of two 25-microgram doses, a quarter of what adults receive, showed only modest effectiveness against COVID infection. The trial, which largely took place when Omicron was the dominant variant, showed that the vaccine’s efficacy against symptomatic infections was 43.7 percent in children 6 months to 2 years old and 37.5 percent in children ages 2 to 5.

Though children infected with COVID typically become less severely ill than adults, more than 1,000 children under 18 have died over the course of the pandemic, including 350 children under 5, according to CDC data. COVID’s long-term effects on children are still unknown. “Given the need for a vaccine against COVID-19 in infants and young children we are working with the U.S. FDA and regulators globally to submit these data as soon as possible,” said Moderna CEO Stéphane Bancel.

 

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